The Occurrence of Megaloblastic Erythropoiesis in Patients with Hemochromatosis
نویسنده
چکیده
By B. J. KOSZEW’SKI, M.D. H YPERCHROMIC megaloblastic anemia is not a disease entity. Besides the pernicious anemia of Addison-Biermer w’hich is due to a lack of Castie’s intrinsic principle in the gastric juice, there is a series of illnesses that cat lead to the deficiency of the atltianemic principle atld subsequently typical hematologic changes. According to Castle and Mitlot.,’3 Rohr,5#{176}Wintrobe,7#{176} Bernard,5 WilkinsolsH atld other investigators one can classify these symptomatic anemias by a consideration of the factors which initiate the onset, such as dietary de-
منابع مشابه
Megaloblastic Anaemia in Haemochromatosis.
IN 1877 Muller described a marked bronzed discoloration of the skin in some patients considered to have pernicious anaemia. This observation, confirmed later by Immerman (1879) is likely to be the first record of an association between a macrocytic type of anemia and haemochromatosis. Since that time French (1909), Roth (1915), Bork (1928), Cain (1940), Hotz (1944) and Harvier and Mallarme (193...
متن کاملNephrotic Syndrome Due to Thrombosis of the Inferior Vena Cava and Renal Veins.
Excretion in Hepatic Cirrhosis, A.M.A. Arch. intern. Med., 108, 41. FRENCH, H. (1909): Sixty Cases of Pernicious Anaemia, Guy's Hosp. Rep., 63, 2. GRANVILLE, N., and DAMESHEK, W. (1958): Haemochromatosis with Megaloblastic Anaemia. Response to Folic Acid Therapy, New Engl. J. Med., 258, 586. HARVIER, P., and MALLARME, J. (1938): Biermer Disease of Hepatomegalic Form with Pigmentations Simulatin...
متن کاملFolic-acid Deficiency and Megaloblastic Erythropoiesis in Myelofibrosis.
Folic-acid deficiency may arise in conditions which produce an increased demand for the vitamin. Diseases in this category include acute leukaemia, disseminated carcinomatosis (Girdwood, 1959), myelofibrosis (Chanarin, Mollin, and Anderson, 1958), and haemolytic anaemia (Chanarin, Dacie, and Mollin, 1959). The presence of megaloblastic erythropoiesis in myelofibrosis has been described in only ...
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By ULFAR JONSSON, 0. STUART ROATH AND CHARLOTFE I. F. KIRKPATRICK BONE MARROW CHANGES suggestive or diagnostic of megaloblastic erythropoiesis have been recognized on a number of occasions in patients with hemolytic anemia. 4 ln many of these patients evalumation of a possible response to agents effective in megaloblastic anemias has not been possible because of concurrent transfusions or for o...
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تاریخ انتشار 2005